Research

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There has been significant research with numerous, well-documented health benefits of cranberries and Type-A Proanthocyanidins (A-PACs).

Below, please find a selection of scientific studies and research articles* for your education.  

Cranberries & Type-A Proanthocyanidins (A-PACs)

American cranberries and health benefits - an evolving story of 25 years
Anti-Adhesion Activity of A2-type Proanthocyanidins (a Cranberry Major Component) on Uropathogenic E. coli and P. mirabilis Strains
Anti-inflammatory and macrophage polarization effects of Cranberry Proanthocyanidins (PACs) for periodontal and peri-implant disease therapy
Are High Proanthocyanidins Key to Cranberry Efficacy in the Prevention of Recurrent Urinary Tract Infection
A-type cranberry proanthocyanidins and uropathogenic bacterial anti-adhesion activity
Bioactive Components of Polyphenol-Rich and Non-Polyphenol-Rich Cranberry Fruit Extracts and Their Chemopreventive Effects on Colitis-Associated Colon Cancer
Bioactive compounds in cranberries and their biological properties
Bioactive compounds in cranberries and their role in prevention of urinary tract infections
Bioactive Compounds, Antioxidant Activity, and Biological Effects of European Cranberry ( Vaccinium oxycoccos)
Can Cranberries Contribute to Reduce the Incidence of Urinary Tract Infections - a Systematic Review with Meta-Analysis
Clinical applications of cranberry in urinary tract infections
Consumption of a cranberry juice beverage lowered the number of clinical urinary tract infection episodes in women with a recent history of urinary tract infection
Consumption of cranberry as adjuvant therapy for urinary tract infections in susceptible populations - a systematic review
Cranberries - ripe for more cancer research
Cranberries (Vaccinium macrocarpon) and cardiovascular disease risk factors
Cranberries and cranberry products - powerful in vitro, ex vivo, and in vivo sources of antioxidants
Cranberries and lower urinary tract infection prevention
Cranberries and Their Bioactive Constituents in Human Health
Cranberries for preventing urinary tract infections
Cranberry - Chemical Composition, Antioxidant Activity and Impact on Human Health
Cranberry (Vaccinium macrocarpon) Extract Impairs Nairovirus Infection by Inhibiting the Attachment to Target Cells
Cranberry and recurrent cystitis - more than marketing
Cranberry A-type proanthocyanidins selectively target acute myeloid leukemia cells
Cranberry capsules reduce the risk of postoperative urinary tract infection in women undergoing benign gynaecological surgery
Cranberry components for the therapy of infectious disease
Cranberry juice - a well-characterized folk-remedy against bacterial urinary tract infection
Cranberry juice and urinary tract infection
Cranberry juice capsules and urinary tract infection after surgery - results of a randomized trial
Cranberry juice for the prevention of pediatric urinary tract infection - a randomized controlled trial
Cranberry polyphenols - potential benefits for dental caries and periodontal disease
Cranberry Polyphenols and Prevention against Urinary Tract Infections - Relevant Considerations
Cranberry proanthocyanidins - natural weapons against periodontal diseases
Cranberry Proanthocyanidins - Protein complexes for macrophage activation
Cranberry proanthocyanidins and the maintenance of urinary tract health
Cranberry proanthocyanidins are cytotoxic to human cancer cells and sensitize platinum-resistant ovarian cancer cells to paraplatin
Cranberry proanthocyanidins have anti-biofilm properties against Pseudomonas aeruginosa
Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction
Cranberry proanthocyanidins inhibit the adherence properties of Candida albicans and cytokine secretion by oral epithelial cells
Cranberry Proanthocyanidins Neutralize the Effects of Aggregatibacter actinomycetemcomitans Leukotoxin
Cranberry products for urinary tract infections
Cranberry Reduces the Risk of Urinary Tract Infection Recurrence in Otherwise Healthy Women - A Systematic Review and Meta-Analysis
Cranberry supplementation in the prevention of non-severe lower urinary tract infections
Cranberry-derived proanthocyanidins induce a differential transcriptomic response within Candida albicans urinary biofilms
Current clinical status on the preventive effects of cranberry consumption against urinary tract infections
Daily consumption of cranberry improves endothelial function in healthy adults - a double blind randomized controlled trial
Diagnosis and management of urinary tract infection in older adults
Dietary proanthocyanidins - occurrence, dietary intake, bioavailability, and protection against cardiovascular disease
Does cranberry have a role in catheter-associated urinary tract infections
Effect of oral cranberry extract (standardized proanthocyanidin-A) in patients with recurrent UTI by pathogenic E. coli
Enhancing health benefits of berries through phenolic antioxidant enrichment - focus on cranberry
Evidences of the cardioprotective potential of fruits - the case of cranberries
Flavonoids and phenolic acids from cranberry juice are bioavailable and bioactive in healthy older adults
Healthy properties of proanthocyanidins
High dose versus low dose standardized cranberry proanthocyanidin extract for the prevention of recurrent urinary tract infection in healthy women
Impact of Cranberries on Gut Microbiota and Cardiometabolic Health
Methods to determine effects of cranberry proanthocyanidins on extraintestinal infections - relevance for urinary tract health
Non-Antibiotic Prophylaxis for Urinary Tract Infections
Overview on cranberry and urinary tract infections in females
Phytochemical Compounds and Antioxidant Activity in Different Cultivars of Cranberry (Vaccinium Macrocarpon L)
Phytochemicals of cranberries and cranberry products - characterization, potential health effects, and processing stability
Potential of cranberry-based herbal synergies for diabetes and hypertension management
Prevention of urinary tract infections with vaccinium products
Proanthocyanidin-enriched cranberry extract induces resilient bacterial community dynamics in a gnotobiotic mouse model
Proanthocyanidin-rich extracts from cranberry fruit selectively inhibit the growth of human pathogenic fungi Candida spp. and Cryptococcus neoformans
Proanthocyanidins - a final frontier in flavonoid research
Proanthocyanidins - Components, Pharmacokinetics and Biomedical Properties
Proanthocyanidins - Oligomeric Structures with Unique Biochemical Properties and Great Therapeutic Promise
Proanthocyanidins - Will they effectively restrain conspicuous bacterial strains devolving on urinary tract infection
Proanthocyanidins in health care - current and new trends
Proanthocyanidins Should Be a Candidate in the Treatment of Cancer, Cardiovascular Diseases and Lipid Metabolic Disorder
Propolis potentiates the effect of cranberry (Vaccinium macrocarpon) against the virulence of uropathogenic Escherichia coli
Quantifying and characterizing proanthocyanidins in cranberries in relation to urinary tract health
Ratio of A-type to B-type proanthocyanidin interflavan bonds affects extra-intestinal pathogenic Escherichia coli invasion of gut epithelial cells
Recurrent urinary tract infections in older people - the role of cranberry products
Role of cranberry on bacterial adhesion forces and implications for Escherichia coli-uroepithelial cell attachment
Short-term effects of a dietary supplement on lower urinary tract symptoms
Some New Findings Regarding the Antiadhesive Activity of Cranberry Phenolic Compounds and Their Microbial-Derived Metabolites against Uropathogenic Bacteria
Standardised high dose versus low dose cranberry Proanthocyanidin extracts for the prevention of recurrent urinary tract infection in healthy women
Strategies for prevention of urinary tract infections in neurogenic bladder dysfunction
Synthesis of A-Type Proanthocyanidins and Their Analogues - A Comprehensive Review
The Diverse Efficacy of Food-Derived Proanthocyanidins for Middle-Aged and Elderly Women
The effects of training and the use of cranberry capsule in preventing urinary tract infections after urostomy
Total cranberry extract versus its phytochemical constituents - antiproliferative and synergistic effects against human tumor cell lines
Vaccinium macrocarpon - an interesting option for women with recurrent urinary tract infections and other health benefits

*We take intellectual property rights very seriously. Kindly note that neither CellFend nor any of our affiliates nor subsidiaries were involved with the funding or publication of any of these studies or articles. As such, there are no conflicts that arise. All intellectual and property rights belong to either the respective author(s) or the journal. This product is neither associated with nor endorsed by any of the respective author(s) or the journals cited above. These studies and articles are cited in their original form under the Open Access policy of the Fair Use law. If you are an author or journal representative of one of the aforementioned studies or articles, and if you believe that any of the above publications have been posted in violation of copyright, please contact us. It is not our intent to violate anyone's intellectual property rights. Therefore, we will carefully evaluate any take-down requests we receive and advise of our findings. In the event our analysis determines there exists a potential violation of intellectual property rights, we will act on it immediately.